UBE2W (NM_018299) Human Mass Spec Standard

Specifications

Product Data
Description	UBE2W MS Standard C13 and N15-labeled recombinant protein (NP_060769)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204985
Predicted MW	17.3 kDa
Protein Sequence	Sequence Link (showhide) >RC204985 protein sequence Red=Cloning site Green=Tags(s) MASMQKRLQKELLALQNDPPPGMTLNEKSVQNSITQWIVDMEGAPGTLYEGEKFQLLFKFSSRYPFDSPQ VMFTGENIPVHPHVYSNGHICLSILTEDWSPALSVQSVCLSIISMLSSCKEKRRPPDNSFYVRTCNKNPK KTKWWYHDDTC TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_060769
RefSeq Size	8426
RefSeq ORF	453
Synonyms	UBC-16; UBC16
Locus ID	55284
Cytogenetics	8q21.11
Summary	This gene encodes a nuclear-localized ubiquitin-conjugating enzyme (E2) that, along with ubiquitin-activating (E1) and ligating (E3) enzymes, coordinates the addition of a ubiquitin moiety to existing proteins. The encoded protein promotes the ubiquitination of Fanconi anemia complementation group proteins and may be important in the repair of DNA damage. There is a pseudogene for this gene on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Protein Families	Transcription Factors
Protein Pathways	Ubiquitin mediated proteolysis

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