Kallistatin (SERPINA4) (NM_006215) Human Mass Spec Standard

Specifications

Product Data
Description	SERPINA4 MS Standard C13 and N15-labeled recombinant protein (NP_006206)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC204941
Predicted MW	48.5 kDa
Protein Sequence	Sequence Link (showhide) >RC204941 protein sequence Red=Cloning site Green=Tags(s) MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASET PGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVG SALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLV NYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFIL PNQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSG ITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK VVDPTKP SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_006206
RefSeq Size	1700
RefSeq ORF	1281
Synonyms	KAL; kallistatin; KLST; KST; PI-4; PI4
Locus ID	5267
Cytogenetics	14q32.13
Summary	Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome, Secreted Protein

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