CEACAM1 (NM_001024912) Human Mass Spec Standard

CAT#: PH304901

CEACAM1 MS Standard C13 and N15-labeled recombinant protein (NP_001020083)



  View other "CEACAM1" proteins (8)

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CNY 14,250.00


货期*
5周

规格
    • 10 ug

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Transient overexpression lysate of carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) (CEACAM1), transcript variant 3
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Specifications

Product Data
Description CEACAM1 MS Standard C13 and N15-labeled recombinant protein (NP_001020083)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204901
Predicted MW 51.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001020083
RefSeq Size 3475
RefSeq ORF 1404
Synonyms BGP; BGP1; BGPI
Locus ID 634
Cytogenetics 19q13.2
Summary This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq, May 2010]
Protein Families Druggable Genome, Transmembrane
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