S100 alpha 6 (S100A6) (NM_014624) Human Mass Spec Standard

Specifications

Product Data
Description	S100A6 MS Standard C13 and N15-labeled recombinant protein (NP_055439)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203951
Predicted MW	10.2 kDa
Protein Sequence	Sequence Link (showhide) >RC203951 protein sequence Red=Cloning site Green=Tags(s) MACPLDQAIGLLVAIFHKYSGREGDKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDLDRNKDQEVNF QEYVTFLGALALIYNEALKG TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_055439
RefSeq Size	683
RefSeq ORF	270
Synonyms	2A9; 5B10; CABP; CACY; PRA; S10A6
Locus ID	6277
Cytogenetics	1q21.3
Summary	The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008]

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