DPM2 (NM_003863) Human Mass Spec Standard

CAT#: PH303919

DPM2 MS Standard C13 and N15-labeled recombinant protein (NP_003854)



  View other "DPM2" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit (DPM2)
    • 100 ug

CNY 3,080.00


DPM2 Antibody - middle region
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Description DPM2 MS Standard C13 and N15-labeled recombinant protein (NP_003854)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC203919
Predicted MW 9.3 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_003854
RefSeq Size 1561
RefSeq ORF 252
Synonyms CDG1U
Locus ID 8818
Cytogenetics 9q34.11
Summary Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1. [provided by RefSeq, Jul 2008]
Protein Families Transmembrane
Protein Pathways Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, Metabolic pathways, N-Glycan biosynthesis
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