LSM10 (NM_032881) Human Mass Spec Standard

Specifications

Product Data
Description	LSM10 MS Standard C13 and N15-labeled recombinant protein (NP_116270)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203562
Predicted MW	14.1 kDa
Protein Sequence	Sequence Link (showhide) >RC203562 protein sequence Red=Cloning site Green=Tags(s) MAVSHSVKERTISENSLIILLQGLQGRVTTVDLRDESVAHGRIDNVDAFMNIRLAKVTYTDRWGHQVKLD DLFVTGRNVRYVHIPDDVNITSTIEQQLQIIHRVRNFGGKGQGRWEFPPKNCK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_116270
RefSeq Size	869
RefSeq ORF	369
Synonyms	MST074; MSTP074
Locus ID	84967
Cytogenetics	1p34.3
Summary	Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.[UniProtKB/Swiss-Prot Function]

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