BANF1 (NM_003860) Human Mass Spec Standard

Specifications

Product Data
Description	BANF1 MS Standard C13 and N15-labeled recombinant protein (NP_003851)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203270
Predicted MW	10.1 kDa
Protein Sequence	Sequence Link (showhide) >RC203270 protein sequence Red=Cloning site Green=Tags(s) MTTSQKHRDFVAEPMGEKPVGSLAGIGEVLGKKLEERGFDKAYVVLGQFLVLKKDEDLFREWLKDTCGAN AKQSRDCFGCLREWCDAFL TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003851
RefSeq Size	1179
RefSeq ORF	267
Synonyms	BAF; BCRP1; D14S1460; NGPS
Locus ID	8815
Cytogenetics	11q13.1
Summary	The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Jan 2009]

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