HES6 (NM_018645) Human Mass Spec Standard

Specifications

Product Data
Description	HES6 MS Standard C13 and N15-labeled recombinant protein (NP_061115)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203205
Predicted MW	24.1 kDa
Protein Sequence	Sequence Link (showhide) >RC203205 protein sequence Red=Cloning site Green=Tags(s) MAPPAAPGRDRVGREDEDGWETRGDRKARKPLVEKKRRARINESLQELRLLLAGAEVQAKLENAEVLELT VRRVQGVLRGRAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHLLESMPLREGSS FQDLLGDALAGPPRAPGRSGWPAGGAPGSPIPSPPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGS LTTAQIARSVWRPW TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_061115
RefSeq Size	1470
RefSeq ORF	672
Synonyms	bHLHb41; bHLHc23; C-HAIRY1; HES-6
Locus ID	55502
Cytogenetics	2q37.3
Summary	This gene encodes a member of a subfamily of basic helix-loop-helix transcription repressors that have homology to the Drosophila enhancer of split genes. Members of this gene family regulate cell differentiation in numerous cell types. The protein encoded by this gene functions as a cofactor, interacting with other transcription factors through a tetrapeptide domain in its C-terminus. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Dec 2008]
Protein Families	Druggable Genome, Transcription Factors

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