COMMD9 (NM_014186) Human Mass Spec Standard

Specifications

Product Data
Description	COMMD9 MS Standard C13 and N15-labeled recombinant protein (NP_054905)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203050
Predicted MW	21.8 kDa
Protein Sequence	Sequence Link (showhide) >RC203050 protein sequence Red=Cloning site Green=Tags(s) MAALTAEHFAALQSLLKASSKDVVRQLCQESFSSSALGLKKLLDVTCSSLSVTQEEAEELLQALHRLTRL VAFRDLSSAEAILALFPENFHQNLKNLLTKIILEHVSTWRTEAQANQISLPRLVDLDWRVDIKTSSDSIS RMAVPTCLLQMKIQEDPSLCGDKPSISAVTVELSKETLDTMLDGLGRIRDQLSAVASK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_054905
RefSeq Size	3006
RefSeq ORF	594
Synonyms	C11orf55; HSPC166; LINC00610
Locus ID	29099
Cytogenetics	11p13
Summary	May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966). Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203).[UniProtKB/Swiss-Prot Function]

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