TSSC3 (PHLDA2) (NM_003311) Human Mass Spec Standard

Specifications

Product Data
Description	PHLDA2 MS Standard C13 and N15-labeled recombinant protein (NP_003302)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202884
Predicted MW	17.1 kDa
Protein Sequence	Sequence Link (showhide) >RC202884 protein sequence Red=Cloning site Green=Tags(s) MKSPDEVLREGELEKRSDSLFQLWKKKRGVLTSDRLSLFPASPRARPKELRFHSILKVDCVERTGKYVYF TIVTTDHKEIDFRCAGESCWNAAIALALIDFQNRRALQDFRSRQERTAPAAPAEDAVAAAAAAPSEPSEP SRPSPQPKPRTP TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003302
RefSeq Size	937
RefSeq ORF	456
Synonyms	BRW1C; BWR1C; HLDA2; IPL; TSSC3
Locus ID	7262
Cytogenetics	11p15.4
Summary	This gene is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver. [provided by RefSeq, Oct 2010]
Protein Families	Druggable Genome

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