Caveolin 2 (CAV2) (NM_001233) Human Mass Spec Standard

Specifications

Product Data
Description	CAV2 MS Standard C13 and N15-labeled recombinant protein (NP_001224)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202703
Predicted MW	18.1 kDa
Protein Sequence	Sequence Link (showhide) >RC202703 representing NM_001233 Red=Cloning site Green=Tags(s) MGLETEKADVQLFMDDDSYSHHSGLEYADPEKFADSDQDRDPHRLNSHLKLGFEDVIAEPVTTHSFDKVW ICSHALFEISKYVMYKFLTVFLAIPLAFIAGILFATLSCLHIWILMPFVKTCLMVLPSVQTIWKSVTDVI IAPLCTSVGRCFSSVSLQLSQD TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001224
RefSeq Size	3332
RefSeq ORF	486
Synonyms	CAV
Locus ID	858
Cytogenetics	7q31.2
Summary	The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011]
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Focal adhesion

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