MPST (NM_001013436) Human Mass Spec Standard

CAT#: PH302466

MPST MS Standard C13 and N15-labeled recombinant protein (NP_001013454)



  View other "MPST" proteins (15)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of mercaptopyruvate sulfurtransferase (MPST), nuclear gene encoding mitochondrial protein, transcript variant 1
    • 100 ug

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Specifications

Product Data
Description MPST MS Standard C13 and N15-labeled recombinant protein (NP_001013454)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202466
Predicted MW 33.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001013454
RefSeq Size 1371
RefSeq ORF 891
Synonyms MST; TST2; TUM1
Locus ID 4357
Cytogenetics 22q12.3
Summary This protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Cysteine and methionine metabolism, Metabolic pathways
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