Carbonic Anhydrase II (CA2) (NM_000067) Human Mass Spec Standard

Specifications

Product Data
Description	CA2 MS Standard C13 and N15-labeled recombinant protein (NP_000058)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201974
Predicted MW	29.2 kDa
Protein Sequence	Sequence Link (showhide) >RC201974 protein sequence Red=Cloning site Green=Tags(s) MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEF DDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGL AVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFAARGLLPESLDYWTYPGSLTTPPLLECVTWIV LKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_000058
RefSeq Size	1666
RefSeq ORF	780
Synonyms	CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282
Locus ID	760
Cytogenetics	8q21.2
Summary	The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Protein Families	Druggable Genome
Protein Pathways	Nitrogen metabolism

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