XTP3TPA (DCTPP1) (NM_024096) Human Mass Spec Standard

Specifications

Product Data
Description	DCTPP1 MS Standard C13 and N15-labeled recombinant protein (NP_077001)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201727
Predicted MW	18.7 kDa
Protein Sequence	Sequence Link (showhide) >RC201727 protein sequence Red=Cloning site Green=Tags(s) MSVAGGEIRGDTGGEDTAAPGRFSFSPEPTLEDIRRLHAEFAAERDWEQFHQPRNLLLALVGEVGELAEL FQWKTDGEPGPQGWSPRERAALQEELSDVLIYLVALAARCRVDLPLAVLSKMDINRRRYPAHLARSSSRK YTELPHGAISEDQAVGPADIPCDSTGQTST TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_077001
RefSeq Size	1143
RefSeq ORF	510
Synonyms	CDA03; RS21C6; XTP3TPA
Locus ID	79077
Cytogenetics	16p11.2
Summary	The protein encoded by this gene is dCTP pyrophosphatase, which converts dCTP to dCMP and inorganic pyrophosphate. The encoded protein also displays weak activity against dTTP and dATP, but none against dGTP. This protein may be responsible for eliminating excess dCTP after DNA synthesis and may prevent overmethylation of CpG islands. Three transcript variants, one protein-coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]
Protein Families	Stem cell - Pluripotency

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