SPOP (NM_001007229) Human Mass Spec Standard

CAT#: PH301551

SPOP MS Standard C13 and N15-labeled recombinant protein (NP_001007230)



  View other "SPOP" proteins (11)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of speckle-type POZ protein (SPOP), transcript variant 2
    • 100 ug

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Specifications

Product Data
Description SPOP MS Standard C13 and N15-labeled recombinant protein (NP_001007230)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201551
Predicted MW 42.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001007230
RefSeq Size 2982
RefSeq ORF 1122
Synonyms BTBD32; NEDMACE; NEDMIDF; NSDVS1; NSDVS2; TEF2
Locus ID 8405
Cytogenetics 17q21.33
Summary This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
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