FVT1 (KDSR) (NM_002035) Human Mass Spec Standard

CAT#: PH301153

KDSR MS Standard C13 and N15-labeled recombinant protein (NP_002026)



  View other "FVT1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of 3-ketodihydrosphingosine reductase (KDSR)
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KDSR Antibody - N-terminal region
    • 100 ul

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Specifications

Product Data
Description KDSR MS Standard C13 and N15-labeled recombinant protein (NP_002026)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201153
Predicted MW 36.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002026
RefSeq Size 5198
RefSeq ORF 996
Synonyms DHSR; EKVP4; FVT1; SDR35C1
Locus ID 2531
Cytogenetics 18q21.33
Summary The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Transmembrane
Protein Pathways Metabolic pathways, Sphingolipid metabolism
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