PSMC3IP (NM_013290) Human Mass Spec Standard

Specifications

Product Data
Description	PSMC3IP MS Standard C13 and N15-labeled recombinant protein (NP_037422)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC201045
Predicted MW	23.6 kDa
Protein Sequence	Sequence Link (showhide) >RC201045 protein sequence Red=Cloning site Green=Tags(s) MSKGRAEAAAGAAGILLRYLQEQNRPYSSQDVFGNLQREHGLGKAVVVKTLEQLAQQGKIKEKMYGKQKI YFADQDQFDMVSDADLQVLDGKIVALTAKVQSLQQSCRYMEAEMQKEIQELKKECAGYRERLKNIKAATN HVTPEEKEQVYRERQKYCKEWRKRKRMATELSDAILEGYPKSKKQFFEEVGIETDEDYNVTLPDP TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_037422
RefSeq Size	1440
RefSeq ORF	615
Synonyms	GT198; HOP2; HUMGT198A; ODG3; TBPIP
Locus ID	29893
Cytogenetics	17q21.2
Summary	This gene encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-activate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Protein Families	Druggable Genome

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