PTPN7 (NM_002832) Human Mass Spec Standard

CAT#: PH300699

PTPN7 MS Standard C13 and N15-labeled recombinant protein (NP_002823)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
PTPN7 (HePTP) mouse monoclonal antibody, clone OTI3B10 (formerly 3B10)
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Transient overexpression lysate of protein tyrosine phosphatase, non-receptor type 7 (PTPN7), transcript variant 2
    • 100 ug

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Specifications

Product Data
Description PTPN7 MS Standard C13 and N15-labeled recombinant protein (NP_002823)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200699
Predicted MW 45 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002823
RefSeq Size 3772
RefSeq ORF 1197
Synonyms BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI
Locus ID 5778
Cytogenetics 1q32.1
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2010]
Protein Families Druggable Genome, Phosphatase
Protein Pathways MAPK signaling pathway
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