OAS1 (NM_002534) Human Mass Spec Standard
CAT#: PH300696
OAS1 MS Standard C13 and N15-labeled recombinant protein (NP_002525)
View other "OAS1" proteins (5)
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CNY 19,520.00
Specifications
Product Data | |
Description | OAS1 MS Standard C13 and N15-labeled recombinant protein (NP_002525) |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC200696 |
Predicted MW | 41.8 kDa |
Protein Sequence |
>RC200696 protein sequence
Red=Cloning site Green=Tags(s) MMDLRNTPAKSLDKFIEDYLLPDTCFRMQINHAIDIICGFLKERCFRGSSYPVCVSKVVKGGSSGKGTTL RGRSDADLVVFLSPLTTFQDQLNRRGEFIQEIRRQLEACQRERAFSVKFEVQAPRWGNPRALSFVLSSLQ LGEGVEFDVLPAFDALGQLTGSYKPNPQIYVKLIEECTDLQKEGEFSTCFTELQRDFLKQRPTKLKSLIR LVKHWYQNCKKKLGKLPPQYALELLTVYAWERGSMKTHFNTAQGFRTVLELVINYQQLCIYWTKYYDFKN PIIEKYLRRQLTKPRPVILDPADPTGNLGGGDPKGWRQLAQEAEAWLNYPCFKNWDGSPVSSWILLVRPP ASSLPFIPAPLHEA TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Reference Data | |
RefSeq | NP_002525 |
RefSeq Size | 1470 |
RefSeq ORF | 1092 |
Synonyms | E18/E16; IFI-4; OIAS; OIASI |
Locus ID | 4938 |
Cytogenetics | 12q24.13 |
Summary | This gene is induced by interferons and encodes a protein that synthesizes 2',5'-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12. [provided by RefSeq, Feb 2016] |
Protein Families | Druggable Genome |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC413832 | OAS1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC419268 | OAS1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY413832 | Transient overexpression lysate of 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 1 |
CNY 3,080.00 |
|
LY419268 | Transient overexpression lysate of 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2 |
CNY 3,080.00 |
|
TP300696 | Recombinant protein of human 2',5'-oligoadenylate synthetase 1, 40/46kDa (OAS1), transcript variant 2, 20 µg |
CNY 2,900.00 |