PCLAF (NM_014736) Human Mass Spec Standard

Specifications

Product Data
Description	KIAA0101 MS Standard C13 and N15-labeled recombinant protein (NP_055551)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200694
Predicted MW	12 kDa
Protein Sequence	Sequence Link (showhide) >RC200694 protein sequence Red=Cloning site Green=Tags(s) MVRTKADSVPGTYRKVVAARAPRKVLGSSTSATNSTSVSSRKAENKYAGGNPVCVRPTPKWQKGIGEFFR LSPKDSEKENQIPEEAGSSGLGKAKRKACPLQPDHTNDEKE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_055551
RefSeq Size	1515
RefSeq ORF	333
Synonyms	KIAA0101; L5; NS5ATP9; OEATC; OEATC-1; OEATC1; p15(PAF); p15/PAF; p15PAF; PAF; PAF15
Locus ID	9768
Cytogenetics	15q22.31
Summary	PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.[UniProtKB/Swiss-Prot Function]
Protein Families	Druggable Genome

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