HDAC3 (NM_003883) Human Mass Spec Standard
CAT#: PH300605
HDAC3 MS Standard C13 and N15-labeled recombinant protein (NP_003874)
View other "HDAC3" proteins (3)
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CNY 19,520.00
Specifications
Product Data | |
Description | HDAC3 MS Standard C13 and N15-labeled recombinant protein (NP_003874) |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC200605 |
Predicted MW | 48.8 kDa |
Protein Sequence |
>RC200605 protein sequence
Red=Cloning site Green=Tags(s) MAKTVAYFYDPDVGNFHYGAGHPMKPHRLALTHSLVLHYGLYKKMIVFKPYQASQHDMCRFHSEDYIDFL QRVSPTNMQGFTKSLNAFNVGDDCPVFPGLFEFCSRYTGASLQGATQLNNKICDIAINWAGGLHHAKKFE ASGFCYVNDIVIGILELLKYHPRVLYIDIDIHHGDGVQEAFYLTDRVMTVSFHKYGNYFFPGTGDMYEVG AESGRYYCLNVPLRDGIDDQSYKHLFQPVINQVVDFYQPTCIVLQCGADSLGCDRLGCFNLSIRGHGECV EYVKSFNIPLLVLGGGGYTVRNVARCWTYETSLLVEEAISEELPYSEYFEYFAPDFTLHPDVSTRIENQN SRQYLDQIRQTIFENLKMLNHAPSVQIHDVPADLLTYDRTDEADAEERGPEENYSRPEAPNEFYDGDHDN DKESDVEI TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Reference Data | |
RefSeq | NP_003874 |
RefSeq Size | 1965 |
RefSeq ORF | 1284 |
Synonyms | HD3; KDAC3; RPD3; RPD3-2 |
Locus ID | 8841 |
Cytogenetics | 5q31.3 |
Summary | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Transcription Factors |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC401280 | HDAC3 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY401280 | Transient overexpression lysate of histone deacetylase 3 (HDAC3) |
CNY 3,080.00 |
|
TP300605 | Recombinant protein of human histone deacetylase 3 (HDAC3), 20 µg |
CNY 2,900.00 |