PDZK1 (NM_002614) Human Mass Spec Standard

CAT#: PH300444

PDZK1 MS Standard C13 and N15-labeled recombinant protein (NP_002605)



  View other "PDZK1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description PDZK1 MS Standard C13 and N15-labeled recombinant protein (NP_002605)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200444
Predicted MW 57.1 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002605
RefSeq Size 2301
RefSeq ORF 1557
Synonyms CAP70; CLAMP; NHERF-3; NHERF3; PDZD1
Locus ID 5174
Cytogenetics 1q21.1
Summary This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
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