APEX2 (NM_014481) Human Mass Spec Standard

CAT#: PH300320

APEX2 MS Standard C13 and N15-labeled recombinant protein (NP_055296)



  View other "APEX2" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
Transient overexpression lysate of APEX nuclease (apurinic/apyrimidinic endonuclease) 2 (APEX2), nuclear gene encoding mitochondrial protein
    • 100 ug

CNY 3,080.00


APEX2 Antibody - C-terminal region
    • 100 ul

CNY 5,250.00

Specifications

Product Data
Description APEX2 MS Standard C13 and N15-labeled recombinant protein (NP_055296)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200320
Predicted MW 57.4 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_055296
RefSeq Size 2095
RefSeq ORF 1554
Synonyms APE2; APEXL2; XTH2; ZGRF2
Locus ID 27301
Cytogenetics Xp11.21
Summary Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
Protein Families Druggable Genome
Protein Pathways Base excision repair
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