MDH1 (NM_005917) Human Mass Spec Standard
CAT#: PH300298
MDH1 MS Standard C13 and N15-labeled recombinant protein (NP_005908)
View other "MDH1" proteins (6)
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CNY 19,520.00
Specifications
Product Data | |
Description | MDH1 MS Standard C13 and N15-labeled recombinant protein (NP_005908) |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC200298 |
Predicted MW | 36.4 kDa |
Protein Sequence |
>RC200298 protein sequence
Red=Cloning site Green=Tags(s) MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIA TDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTA SKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVY EALKDDSWLKGEFVTTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGV PDDLLYSFPVVIKNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFLSSA TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Reference Data | |
RefSeq | NP_005908 |
RefSeq Size | 1665 |
RefSeq ORF | 1002 |
Synonyms | DEE88; EIEE88; HEL-S-32; KAR; MDH-s; MDHA; MGC:1375; MOR2 |
Locus ID | 4190 |
Cytogenetics | 2p15 |
Summary | This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6. [provided by RefSeq, Feb 2016] |
Protein Families | Druggable Genome |
Protein Pathways | Citrate cycle (TCA cycle), Glyoxylate and dicarboxylate metabolism, Metabolic pathways, Pyruvate metabolism |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC401788 | MDH1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC434177 | MDH1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY401788 | Transient overexpression lysate of malate dehydrogenase 1, NAD (soluble) (MDH1) |
CNY 3,080.00 |
|
LY434177 | Transient overexpression lysate of malate dehydrogenase 1, NAD (soluble) (MDH1), transcript variant 1 |
CNY 3,080.00 |
|
TP300298 | Recombinant protein of human malate dehydrogenase 1, NAD (soluble) (MDH1), 20 µg |
CNY 2,900.00 |
|
TP720248 | Recombinant protein of human malate dehydrogenase 1, NAD (soluble) (MDH1), transcript variant 1. |
CNY 3,140.00 |