PDCD10 (NM_007217) Human Mass Spec Standard

CAT#: PH300235

PDCD10 MS Standard C13 and N15-labeled recombinant protein (NP_009148)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description PDCD10 MS Standard C13 and N15-labeled recombinant protein (NP_009148)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200235
Predicted MW 24.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_009148
RefSeq Size 1454
RefSeq ORF 636
Synonyms CCM3; TFAR15
Locus ID 11235
Cytogenetics 3q26.1
Summary This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
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