CRABP2 (NM_001878) Human Mass Spec Standard

Specifications

Product Data
Description	CRABP2 MS Standard C13 and N15-labeled recombinant protein (NP_001869)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200221
Predicted MW	15.7 kDa
Protein Sequence	Sequence Link (showhide) >RC200221 protein sequence Red=Cloning site Green=Tags(s) MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVRTTEINFKVGE EFEEQTVDGRPCKSLVKWESENKMVCEQKLLKGEGPKTSWTRELTNDGELILTMTADDVVCTRVYVRE TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001869
RefSeq Size	1088
RefSeq ORF	414
Synonyms	CRABP-II; RBP6
Locus ID	1382
Cytogenetics	1q23.1
Summary	This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2010]
Protein Families	Druggable Genome, Transcription Factors

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