SIRT5 (NM_012241) Human Mass Spec Standard

CAT#: PH300189

SIRT5 MS Standard C13 and N15-labeled recombinant protein (NP_036373)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description SIRT5 MS Standard C13 and N15-labeled recombinant protein (NP_036373)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC200189
Predicted MW 33.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_036373
RefSeq Size 4538
RefSeq ORF 930
Synonyms SIR2L5
Locus ID 23408
Cytogenetics 6p23
Summary This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2010]
Protein Families Druggable Genome, Transcription Factors
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