EXOSC3 (NM_016042) Human Mass Spec Standard

Specifications

Product Data
Description	EXOSC3 MS Standard C13 and N15-labeled recombinant protein (NP_057126)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200035
Predicted MW	29.6 kDa
Protein Sequence	Sequence Link (showhide) >RC200035 protein sequence Red=Cloning site Green=Tags(s) MAEPASVAAESLAGSRARAARTVLGQVVLPGEELLLPEQEDAEGPGGAVERPLSLNARACSRVRVVCGPG LRRCGDRLLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPAS LSYLSFEGATKRNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKL LAPDCEIIQEVGKLYPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHMTSDQRKQIFSRLAES TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_057126
RefSeq Size	1857
RefSeq ORF	825
Synonyms	bA3J10.7; CGI-102; hRrp-40; p10; PCH1B; RRP40; Rrp40p
Locus ID	51010
Cytogenetics	9p13.2
Summary	This gene encodes a non-catalytic component of the human exosome, a complex with 3'-5' exoribonuclease activity that plays a role in numerous RNA processing and degradation activities. Related pseudogenes of this gene are found on chromosome 19 and 21. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2012]
Protein Families	Stem cell - Pluripotency
Protein Pathways	RNA degradation

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