TMX2 (NM_015959) Human Mass Spec Standard

Specifications

Product Data
Description	TMX2 MS Standard C13 and N15-labeled recombinant protein (NP_057043)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200032
Predicted MW	34 kDa
Protein Sequence	Sequence Link (showhide) >RC200032 protein sequence Red=Cloning site Green=Tags(s) MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWREVEILM FLSAIVMMKNRRSITVEQHIGNIFMFSKVANTILFFRLDIRMGLLYITLCIVFLMTCKPPLYMGPEYIKY FNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVDVGRYTDVSTRYKVST SPLTKQLPTLILFQGGKEAMRRPQIDKKGRAVSWTFSEENVIREFNLNELYQRAKKLSKAGDNIPEEQPV ASTPTTVSDGENKKDK TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_057043
RefSeq Size	1741
RefSeq ORF	888
Synonyms	CGI-31; NEDMCMS; PDIA12; PIG26; TXNDC14
Locus ID	51075
Cytogenetics	11q12.1
Summary	This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, one transmembrane domain and a C-terminal ER-retention sequence. This protein is enriched on the mitochondria-associated-membrane of the ER via palmitoylation of two of its cytosolically exposed cysteines. [provided by RefSeq, Jan 2017]
Protein Families	Druggable Genome, Transmembrane

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