Tnfrsf12a Mouse Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA	mBFP-Neo
Symbol	Tnfrsf12a
Locus ID	27279
Kit Components	KN317976G1, Tnfrsf12a gRNA vector 1 in pCas-Guide CRISPR vector KN317976G2, Tnfrsf12a gRNA vector 2 in pCas-Guide CRISPR vector KN317976BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001161746, NM_013749
Synonyms	AI255180; C87282; Fn14; HPIP; TWEAK-R; TweakR
Summary	Receptor for TNFSF12/TWEAK (By similarity). Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.[UniProtKB/Swiss-Prot Function]

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