Sptlc3 Mouse Gene Knockout Kit (CRISPR)
CAT#: KN316688RB
Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated
HDR-mediated knockout kit validation
CNY 12,260.00
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control |
Donor DNA | RFP-BSD |
Symbol | Sptlc3 |
Locus ID | 228677 |
Kit Components |
KN316688G1, Sptlc3 gRNA vector 1 in pCas-Guide CRISPR vector KN316688G2, Sptlc3 gRNA vector 2 in pCas-Guide CRISPR vector KN316688RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_175467, NM_001356507 |
Synonyms | C130053K05Rik |
Summary | Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. SPT complexes containing SPTLC3 generate shorter chain sphingoid bases compared to complexes containing SPTLC2. The SPTLC1-SPTLC3-SPTSSA isozyme uses C12-CoA, C14-CoA and C16-CoA as substrates, with a slight preference for C14-CoA. On the other hand, the SPTLC1-SPTLC3-SPTSSB has the ability to use a broader range of acyl-CoAs without apparent preference.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN316688 | Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN316688BN | Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN316688LP | Sptlc3 - mouse gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
|
KN516688 | Sptlc3 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
|
GA214019 | Sptlc3 CRISPRa kit - CRISPR gene activation of mouse serine palmitoyltransferase, long chain base subunit 3 |
CNY 12,255.00 |