Nlrp6 Mouse Gene Knockout Kit (CRISPR)

CAT#: KN311056BN

Nlrp6 - mouse gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Nlrp6 Rabbit pAb
    • 100 ul

CNY 2,640.00


Nlrp6 (Myc-DDK-tagged) - Mouse NLR family, pyrin domain containing 6 (cDNA clone MGC:37241 IMAGE:4972485)
    • 10 ug

CNY 3,656.00

Specifications

Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA mBFP-Neo
Symbol Nlrp6
Locus ID 101613
Kit Components

KN311056G1, Nlrp6 gRNA vector 1 in pCas-Guide CRISPR vector

KN311056G2, Nlrp6 gRNA vector 2 in pCas-Guide CRISPR vector

KN311056BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001081389, NM_133946
Synonyms AI504961; Nalp6; Navr/Avr; Pypaf5
Summary The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. [provided by RefSeq, Feb 2013]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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