Inhbb Mouse Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Donor DNA	GFP-puro
Symbol	Inhbb
Locus ID	16324
Kit Components	KN308333G1, Inhbb gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: CAGGACACCTGTACGTCGTG KN308333G2, Inhbb gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: GGTGGACGGTGACTTCCTGG KN308333-D, donor DNA containing left and right homologous arms and GFP-puro functional cassette. Homologous arm and GFP-puro sequences (showhide) pUC vector backbone in gray; Left arm sequence in blue; GFP-puro in green; Right arm in violet GCCCATCACC GCCGCTGCCT CGGGCGGCCG TGTCCTCGCT GCGAGCAGCG ACAGGGCGAG GCGCTCAGGT GCGGTCGCGG GGCCCCAGCC GCAGCGCCCT CCGCAGCGCC GCGCCCGGGG TCTCCGGCAC CTTCGCTTCA GTCTCCAGAG CGACTTGCGC CCGCTGCCGC CTCTTCCCTC CACCTTTCCA GCCCGGCCGA GCCAAGCCAC CGTGCCAGCA CCGCTGCTGC CGCTCCTCGC TTTCGCTTCA CCCCGATCAG GGGGCTGCGG TGGCCCTCGA CGCGGAGAGG ATGGGCAGGC TGCAGATGCC TAGGCGCCCC GAGTCGTCAG CGCGCCACTG ACCCGGCGGT CCCCCCCACC CCCTCACCGC CAGCCCGCGT TCCCTTCTGG TCCCCGCGGC GCCCCTTCTC GGCCGCGCGG GAACCCCCGC GGCCCGGCCG GCCCCCTCCC CCTGCGAGCC GGCGGCGGCG CTCCCGGCAG GCGGGCGGGC GGAGGCCCGG GCGGGGGCGG GGCGGGGCGG TGCGCCCAGA GCCCGGAGCC CGGCCCTGAG CTCGCTTCGC CTCGCCTCGC GGCGGGCGCC CTCGTCGCCA GCGGCGCACC GGCCCAACAT CACGCACGCT GTCCCCAAGG CCGCCATGGT CACGGCCCTG CGCAAGCTGC ACGCCGGCAA GGTGCGCGAG GACGGCCGCG TGGAGATCCC GCACCTCGAC GGCCACGCCA GCCCGGGCGC CGACGGCCAG GAGCGCGTCT CCGAGATCAT CAGCTTTGCA GAGACAGGTG GGTTCGGCCA CAGGGAAGCC AGAGGCGGCC GCGATCCCTC CCTTTTTCCT TCTCCTAGGA AGCCCTGCTG CCTTCACCGC CTCTGCAGCC CGCACGCCCC GAGGGCATTT AGGCTCCGGG CAGAGACGTT CTGCGGTGGC CTTGCGCGCT TCCCAGGGTG GCAGTCCTTT TCTATACTGC GCGCCCAGAC TACAGATCCT TTGCGGCTTC CCTTTCCCTG CAGCAACTGG GAAGCACCCT GCCCTTCATC CTGGCTCACG GGAATTGGGC CCCAGCGCCT CTGGGCGCGC GTCCCCCTCC CGGCAGATGC GCGCAGCCCT GGCTCTGCGG GCACTTGCTT AGTGATTGCT TAATGTTTTT GTTTCCCACG ATCCGAGTGT AGGCTTAGCA GTGTAGAGAT GGAGATGTGT GTGCTTGTTG GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_008381
Summary	This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of the dimeric activin and inhibin protein complexes. These complexes activate and inhibit, respectively, follicle stimulating hormone secretion from the pituitary gland. Homozygous knockout mice for this gene exhibit eyelid defects. [provided by RefSeq, Aug 2016]

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