Foxf2 Mouse Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA	RFP-BSD
Symbol	Foxf2
Locus ID	14238
Kit Components	KN306079G1, Foxf2 gRNA vector 1 in pCas-Guide CRISPR vector KN306079G2, Foxf2 gRNA vector 2 in pCas-Guide CRISPR vector KN306079RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_010225
Synonyms	Fkh20; FREAC2; LUN
Summary	Probable transcription activator for a number of lung-specific genes (PubMed:9676429). Mediates up-regulation of the E3 ligase IRF2BPL and drives ubiquitination and degradation of CTNNB1 (By similarity).[UniProtKB/Swiss-Prot Function]

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