Chd7 Mouse Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA	mBFP-Neo
Symbol	Chd7
Locus ID	320790
Kit Components	KN303251G1, Chd7 gRNA vector 1 in pCas-Guide CRISPR vector KN303251G2, Chd7 gRNA vector 2 in pCas-Guide CRISPR vector KN303251BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001081417, NM_001277149, NM_001033395
Synonyms	A730019I05Rik; Cycn; Cyn; Dz; Edy; Flo; Lda; Mt; Obt; RP23-464N23.1; Todo; WBE1; Whi
Summary	This gene encodes a protein containing two chromodomains and an ATP-binding helicase domain that functions as a regulator of transcription. Mutations in this gene result in an array of development defects, including inner ear problems. Mice defective for this gene exhibit many of the clinical features of the CHARGE syndrome caused by mutations in the homologous gene in human. [provided by RefSeq, Sep 2015]

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