CED6 (GULP1) Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Donor DNA	GFP-puro
Symbol	CED6
Locus ID	51454
Kit Components	KN221580G1, CED6 gRNA vector 1 in pCas-Guide CRISPR vector, Target Sequence: AGCAGGAAGAAAGGTAAGTG KN221580G2, CED6 gRNA vector 2 in pCas-Guide CRISPR vector, Target Sequence: AACTTCATTTCTGGGCCAGG KN221580-D, donor DNA containing left and right homologous arms and GFP-puro functional cassette. Homologous arm and GFP-puro sequences (showhide) pUC vector backbone in gray; Left arm sequence in blue; GFP-puro in green; Right arm in violet CTAAGACAAA GATTGTAGCT AATATCTTCT GAGCTCAATA TGTACCAAAT ACTGTGCCAA GTACTTTCAT ACCTTTCCTA ATGTGTAAAA CAATCTTAAG TGGTAGGTAA TTTTATCCTA TGTTTTAACC ACTGCTCCTA GTATATCACC TGTCTTTGTG ACTTTGTAAT AAACACGAAA CTCTTCTGGG CCTCAGGTAA ATAAAAAGTA AAGTGTTTAT ATACACACCT CTTGTCAACA AGCTGAGGAA AAAGTATTGA TCTTTCTTCT CCTTAAGTTT GCAAATAAAT ATAGTTAATG ATGGATATAT AATAGAAAAA AGACAAAATT GAAGAACTTG GGAGGAATTT CTGTGAGACA TTCCTATCTG CTTGTGCCAC TCACGTTATT AAGTACTTGT GTTTTTTCTT ACCCAATGTC CTTTGAGGCA TTTTAGAATA TTGTTTGTAA ATATTTTTAA AAATTTAAAA AGCCTTTATA ATTAAAACCA CATTAGCAAA AGAGAGGTCA GTCAACAGTC CTTTGTTTAT GTTTTAATAT TTTGTCACTT TTACAGGATT TAAGTCGTGG AACTGAACAT TTATTTGGCT GATCCTCATC AAATCTGCAA ACGTTGCTAA TTAGCTTTCC TTAGTTATCA CCCTAGTGAA AGATCAAAGT TGTTTATTAC ACTGAGTTCA CAATACATAT GTGATAATAT GTCGCCTGGC AACTTGAAGC TTGTTGTGAA ATTGCAAAGA ATAAAATGAT CTGAAACTTT GTCCTAACTT TAGCTTATGT AGCCATATAA TACTAAATTC CCTGGGCTTA CATAAGATTA TGGTAACATA AATTCATTCA TAATTGTGTG TGTGTGTGTG CACAGGCTTC ATGTATCATT GAACAATATG TGAGGATTGG TAGTAGATAG ATTGAAAGCA ATGAGGCCAC AATAAGTTTG TTATTAATTT TTAGGTAGGA ATTTAAATAA CTACGAATGT AGTATATTAT AGTGATCACT ATAGGACTGA AAGAAACAGC TAGTTAGATG TTGTTTTTTA ATGGGCAGAA AAACATGGCA TTTGACAAAC TATTTTATGA TGCACTTATA AAGAAAGATA GAAAAATAAA TATAACTTTG CGTAGGTCAG TGAAGTTTAA ATAATGTATC CTTTCCATTC TCAAAGGAGT TCTCTAGTGG AGAGCATGGG GCTCTCTCCT GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001252668, NM_001252669, NM_016315, NR_045562, NR_045563
Synonyms	CED-6; CED6; GULP
Summary	The protein encoded by this gene is an adapter protein necessary for the engulfment of apoptotic cells by phagocytes. Several transcript variants, some protein coding and some thought not to be protein coding, have been found for this gene. [provided by RefSeq, Nov 2011]

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