Von Willebrand Factor (VWF) Human Gene Knockout Kit (CRISPR)

CAT#: KN218497RB

VWF - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Purified VWF mouse monoclonal antibody, clone OTI6C7 (formerly 6C7)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


VWF (Myc-DDK-tagged)-Human von Willebrand factor (VWF)
    • 10 ug

CNY 18,232.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol Von Willebrand Factor
Locus ID 7450
Kit Components

KN218497G1, Von Willebrand Factor gRNA vector 1 in pCas-Guide CRISPR vector

KN218497G2, Von Willebrand Factor gRNA vector 2 in pCas-Guide CRISPR vector

KN218497RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_000552
Synonyms F8VWF; VWD
Summary This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22. [provided by RefSeq, Oct 2015]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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