VLDL Receptor (VLDLR) Human Gene Knockout Kit (CRISPR)

CAT#: KN211796LP

VLDLR - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Mouse Monoclonal VLDL Receptor Antibody (6A6)
    • 100 ul

CNY 5,381.00


VLDLR (Myc-DDK-tagged)-Human very low density lipoprotein receptor (VLDLR), transcript variant 1
    • 10 ug

CNY 9,592.00

Specifications

Product Data
Format 2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA Luciferase-Puro
Symbol VLDL Receptor
Locus ID 7436
Kit Components

KN211796G1, VLDL Receptor gRNA vector 1 in pCas-Guide CRISPR vector

KN211796G2, VLDL Receptor gRNA vector 2 in pCas-Guide CRISPR vector

KN211796LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001018056, NM_003383, NM_001322225, NM_001322226
Synonyms CAMRQ1; CARMQ1; CHRMQ1; VLDLRCH
Summary The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. This gene encodes a lipoprotein receptor that is a member of the LDLR family and plays important roles in VLDL-triglyceride metabolism and the reelin signaling pathway. Mutations in this gene cause VLDLR-associated cerebellar hypoplasia. Alternative splicing generates multiple transcript variants encoding distinct isoforms for this gene. [provided by RefSeq, Aug 2009]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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