Ceramide synthase 2 (CERS2) Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA	RFP-BSD
Symbol	Ceramide synthase 2
Locus ID	29956
Kit Components	KN200145G1, Ceramide synthase 2 gRNA vector 1 in pCas-Guide CRISPR vector KN200145G2, Ceramide synthase 2 gRNA vector 2 in pCas-Guide CRISPR vector KN200145RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_013384, NM_022075, NM_181746
Synonyms	FLJ10243; L3; MGC987; SP260; TMSG1
Summary	This gene encodes a protein that has sequence similarity to yeast longevity assurance gene 1. Mutation or overexpression of the related gene in yeast has been shown to alter yeast lifespan. The human protein may play a role in the regulation of cell growth. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

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