Mouse Usp51 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Usp51
Locus ID	635253
Kit Components	GA218226G1, Usp51 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA218226G2, Usp51 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA218226G3, Usp51 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001137547
Synonyms	AV136873
Summary	Deubiquitinates histone H2A at 'Lys-13' and 'Lys-15' and regulates DNA damage response. USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1 foci.[UniProtKB/Swiss-Prot Function]

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