Mouse Cers3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cers3
Locus ID	545975
Kit Components	GA217821G1, Cers3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217821G2, Cers3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217821G3, Cers3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001164201
Synonyms	4930550L11Rik; Gm488; Lass3; T3L
Summary	Has (dihydro)ceramide synthesis activity with relatively broad substrate specificity, but a preference for C18:0 and other middle- to long-chain fatty acyl-CoAs. It is crucial for the synthesis of very long-chain ceramides in the epidermis, to maintain epidermal lipid homeostasis and terminal differentiation (By similarity).[UniProtKB/Swiss-Prot Function]

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