Mouse Tlr12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tlr12
Locus ID	384059
Kit Components	GA217277G1, Tlr12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217277G2, Tlr12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217277G3, Tlr12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_205823
Synonyms	Gm1365; Tlr11
Summary	Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Plays a role in preventing infection of internal organs of the urogenital system.[UniProtKB/Swiss-Prot Function]

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