Mouse Zfp488 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zfp488
Locus ID	382867
Kit Components	GA217264G1, Zfp488 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217264G2, Zfp488 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217264G3, Zfp488 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001013777
Synonyms	Gm1206; Znf488
Summary	Transcriptional repressor (PubMed:16908628). Plays a role in oligodendrocyte differentiation, together with OLIG2 (PubMed:16908628, PubMed:22355521). Mediates Notch signaling-activated formation of oligodendrocyte precursors (PubMed:16908628). Promotes differentiation of adult neural stem progenitor cells (NSPCs) into mature oligodendrocytes and contributes to remyelination following nerve injury (PubMed:22355521).[UniProtKB/Swiss-Prot Function]

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