Mouse Morc3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Morc3
Locus ID	338467
Kit Components	GA216943G1, Morc3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216943G2, Morc3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216943G3, Morc3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001045529
Synonyms	1110051N18Rik; AI452146; BF318192; D16Jhu32e; NXP2; Zcwcc3
Summary	Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (By similarity). Sumoylated MORC3-NBs can also associate with PML-NBs (By similarity). Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity (PubMed:17332504). Binds RNA in vitro (By similarity).[UniProtKB/Swiss-Prot Function]

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