Mouse Bend6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Bend6
Locus ID	320705
Kit Components	GA216548G1, Bend6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216548G2, Bend6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216548G3, Bend6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001310484, NM_177235
Synonyms	B230209C24Rik
Summary	Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis (PubMed:23571214, PubMed:25561495).[UniProtKB/Swiss-Prot Function]

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