Mouse Adgrl3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Adgrl3
Locus ID	319387
Kit Components	GA216273G1, Adgrl3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216273G2, Adgrl3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216273G3, Adgrl3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001347367, NM_001347368, NM_001347369, NM_001347371, NM_198702, NM_001359826, NM_001359828, NM_001359829, NM_001359830, NM_001359831, NM_001359832, NM_001359833, NM_001359834
Synonyms	5430402I23Rik; CIRL-3; D130075K09Rik; Gm1379; LEC3; Lphn3; mKIAA0768
Summary	Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells (PubMed:22405201, PubMed:25728924, PubMed:26235031). Plays a role in the development of glutamatergic synapses in the cortex (PubMed:22405201, PubMed:24739570). Important in determining the connectivity rates between the principal neurons in the cortex (PubMed:24739570).[UniProtKB/Swiss-Prot Function]

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