Mouse Nrip1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nrip1
Locus ID	268903
Kit Components	GA215964G1, Nrip1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215964G2, Nrip1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215964G3, Nrip1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_173440, NM_001358238
Synonyms	6030458L20Rik; 8430438I05Rik; 9630050P12; AA959574; AW456757; RIP140
Summary	Modulates transcriptional repression by nuclear hormone receptors such as NR2C1, thyroid hormone receptor and retinoic acid receptor/RARA. Essential for cumulus expansion and follicle rupture during ovulation. Also controls the balance between fat accumulation and energy expenditure. Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC.[UniProtKB/Swiss-Prot Function]

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