Mouse Actr3b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Actr3b
Locus ID	242894
Kit Components	GA215091G1, Actr3b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215091G2, Actr3b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215091G3, Actr3b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001004365, NM_001310504
Synonyms	9630005C02; Arp3b; Arp3beta; ARP11; AW047569
Summary	Plays a role in the organization of the actin cytoskeleton. May function as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. May decrease the metastatic potential of tumors (By similarity).[UniProtKB/Swiss-Prot Function]

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