Mouse Phgdh activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Phgdh
Locus ID	236539
Kit Components	GA214674G1, Phgdh gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214674G2, Phgdh gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214674G3, Phgdh gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_016966
Synonyms	3-PGDH; 3PGDH; 4930479N23; A10; PGAD; PGD; PGDH; SERA
Summary	Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Does not catalyze the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate.[UniProtKB/Swiss-Prot Function]

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