Mouse Crebzf activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Crebzf
Locus ID	233490
Kit Components	GA214458G1, Crebzf gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214458G2, Crebzf gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214458G3, Crebzf gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_145151, NR_073436, NR_073437, NR_073438
Synonyms	1110034C16Rik; 6330417B10Rik; LAZip; LAZipII; SMILE; Zf
Summary	Strongly activates transcription when bound to HCFC1. Suppresses the expression of HSV proteins in cells infected with the virus in a HCFC1-dependent manner. Also suppresses the HCFC1-dependent transcriptional activation by CREB3 and reduces the amount of CREB3 in the cell. Able to down-regulate expression of some cellular genes in CREBZF-expressing cells (By similarity).[UniProtKB/Swiss-Prot Function]

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